Suffering translated to Dukkha (Pāli दुक्ख; Sanskrit दुःख duḥkha).
The Buddha talks about Dukkha:
This, bhikkhus, is the Noble Truth of Dukkha: Birth is dukkha, aging is dukkha, sickness is dukkha, death is dukkha. Presence of objects we loathed is dukkha; separation from what we love is dukkha; not getting what is wanted is dukkha. In short, the five clinging-aggregates are dukkha.
— SN 56.11
Dukkha can refer to various unpleasant experiences ranging from discomfort to pain and suffering. Dukkha is the focus of the Four Noble Truths; the Path Leading to the Cessation of Suffering: (Dukkha Nirodha Gamini Patipada Magga) states,"This is the noble truth of the way leading to the cessation of suffering: it is the Noble Eightfold Path; that is, right view, right intention, right speech, right action, right livelihood, right effort, right mindfulness and right concentration."
Khenpo Dudjom Dorjee teaches on the Truth of the Cessation of Suffering: