"a stranger in a strange land"
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Stranger in a Strange Land
Public DomainStranger in a Strange Land

A science fiction book with this title was published a number of years before The AlchemistStranger in a Strange Land by Robert A. Heinlein was published in 1961.  It tells the story of a man raised by Martians on Mars returning to Earth, where he transforms the culture.

The phrase comes from Exodus:

Moses was content to stay with the man, who gave his daughter Zipporah to Moses in marriage. And she bore him a son, and he called him Gershom, saying, "I have been a stranger in a strange land".

Exodus 2:21-22

Gershom means "exile".