"I was exactly forty three blocks by five blocks away from my hotel"

The streets of New York City are arranged as a grid system, where streets run at right angles to each other.

The plan was devised by a commission set up in 1811 who proposed that New York be divided into 12 avenues running north to south, and 155 streets running east to west, thus creating almost 2,000 blocks. It was further decided that streets and blocks should be given numbers not names. 

The location of the 'Amazon' (Barbizon) in the New York grid system:

Google Map